New paper investigating the role of EGFR signalling in muscle dystrophies

A new year, a new paper! 🥳

We are happy to report that we recently published a paper in the journal “Cell Death & Disease” entitled: “Investigating the role of EGFR signalling in muscle dystrophies: implications for Duchenne muscular dystrophy.

In this work, we uncover previously unknown molecular interactions of EGFR that drive muscle degeneration in Duchenne Muscular Dystrophy. By studying the roles of EGF and EFEMP1 in muscle cells, we identify novel mechanisms that help explain fibrosis and muscle dysfunction.

These insights open the door to targeted therapies that could help slow muscle degeneration in muscle dystrophies.

You can see the paper here: https://www.nature.com/articles/s41419-025-08193-9

Author(s)

Esther Fernández-Simón

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